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Oral Semaglutide

Image is for illustration only. Actual medication labels identify the licensed compounding pharmacy that dispenses your prescription; DirectRxCare is not a pharmacy and does not compound medications.

Needle-Free
  • Needle-free daily tablet
  • GLP-1 appetite suppression
  • Reduces cravings and hunger
  • Discreet and travel-friendly
  • Physician-supervised dosing
  • Unlimited clinical support included
Oral

Oral Semaglutide

Needle-free tablet that helps curb cravings

4.9(127 reviews)

Important Information

  • Already taking this medication? If you are not new to this treatment and need to continue at your current dose or move to a higher dose, you will need to provide supporting documentation (such as a recent prescription, pharmacy label, or provider records) showing you have recently been on it. Without this, your provider will start you at the beginning dose.

Compounded oral Semaglutide tablets deliver GLP-1 appetite suppression and weight loss support without injections.

Doctor-Supervised
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Please note: your medication will arrive in a bottle or vial with the dispensing pharmacy's branding and labeling — packaging may differ from the product image shown.

The Why

Why Oral Semaglutide?

"Because not everyone wants to inject. Oral Semaglutide delivers the same GLP-1 appetite control in a daily tablet — no needles, no syringes, no sharps disposal. Just swallow and go."

"I wanted the benefits of Semaglutide but couldn't get past the needles. The oral tablets have been a game-changer — down 19 lbs and zero injection anxiety."

Jessica T.

Verified Patient

Oral Semaglutide
Research & Facts

The Science Behind Oral Semaglutide

GLP-1 support without the needle

~15%

Avg. weight reduction with high-dose oral semaglutide (OASIS 1)

Daily

Once-a-day tablet

0

Needles required

How It Works

Oral semaglutide works on the same GLP-1 pathway as the injection. It is paired with an absorption enhancer so the medication can be absorbed through the stomach lining when taken on an empty stomach.

Key Facts

  • An oral form of semaglutide was first FDA-approved for type 2 diabetes in 2019.
  • It should be taken with a small sip of water at least 30 minutes before food, drink, or other medicines.
  • Daily dosing keeps steady levels in the body similar to a weekly injection.
  • A great option for people who prefer to avoid injections.

Published Research

OASIS 1 Trial

The Lancet, 2023

In 667 adults with overweight or obesity, once-daily oral semaglutide 50 mg led to an average body-weight reduction of about 15.1% over 68 weeks, versus about 2.4% with placebo.

STEP 1 Trial

New England Journal of Medicine, 2021

In 1,961 adults with overweight or obesity, once-weekly semaglutide 2.4 mg plus lifestyle changes produced an average body-weight reduction of about 14.9% over 68 weeks, versus about 2.4% with placebo.

Research summaries describe published studies of the active ingredient and are provided for education only. Compounded medications are not FDA-approved and were not the products studied. Individual results vary; a licensed provider will determine whether treatment is appropriate for you.

FAQ

Frequently Asked Questions

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